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An introduction to the endogenous cannabinoid system
In orforgliprons study, up to 10% of patients stopped treatment, compared with 3% on placebo
No severe treatment-related adverse events were reported
In the STEP 1 trial published in the New England Journal of Medicine (2021), participants receiving semaglutide 2.4 mg weekly achieved an average weight loss of approximately 15% of body weight over 68 weeks, compared to 2.4% with placebo
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