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Research has shown increased phosphorylation of extracellular signal-regulated kinases (ERK) 1 and 2, along with their downstream targets, including c-Fos, c-Jun, and Egr-1, which are molecules involved in cell growth, migration, and angiogenesis
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BV, another essential bile pigment in BC, exerts anti-inflammatory effects by down-regulating inflammatory mediators expression, including TNF-, IL-6, IL-1, and iNOS mRNA, and negatively regulating heme oxygenase-1 mRNA expression (Li et al., 2017
10.1007/s10620-006-9187-0
Determination of LongR3-IGF-I, R3-IGF-I, Des13 IGF-I and their metabolites in human plasma samples by means of LCMS
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