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The first Phase 3 results from TRIUMPH-4 were announced in December 2025, with seven additional readouts expected throughout 2026

limited direct data Clinical Markers Higher-Risk Groups Individuals with diarrhoea Low whole-food intake Pre-existing suboptimal intake 4.5 Calcium Physiological Role Calcium is essential for: Bone mineralisation Neuromuscular signalling Vascular function Hormonal secretion Dietary calcium is obtained primarily from: Dairy products Fortified plant milks Leafy greens Small fish with bones Why GLP-1 Therapy May Influence Calcium Status Potential mechanisms include: Reduced overall food intake Reduced dairy intake due to nausea or early satiety Reduced dietary fat intake affecting absorption of vitamin D (indirect impact) GLP-1 receptor agonists do not directly impair calcium transporters in the intestine

But because GH and IGF-1 promote cell growth, they could theoretically accelerate existing cancers

10.1016/j.jacc.2021.12.011 31 HermansenK.BkdalT

If your symptoms persist, talk with your doctor about using backup contraception