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Given their efficacy and acceptable safety in adults, GLP-1 RAs became logical candidates for trials in adolescents with obesity, a group with few other medication options

In a randomized controlled trial conducted in 2022, participants in the Wegovy group experienced substantial weight loss, with a 15.8% reduction in body weight

These came with risks, including inconsistent or inaccurate amounts of the active ingredients

Mette Gislum, Christin Lth Hertz and Thomas Bo Jensen are employees of Novo Nordisk A/S

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