When to stay at a dose longer than 4 weeks: You're still losing 1 to 2 pounds per week at the current dose You experienced moderate to severe nausea, vomiting, or diarrhea in the first 2 weeks of the current dose Your provider recommends a slower titration due to age, renal function, or other medications When to increase on schedule: Weight loss has slowed to less than 0.5 pounds per week for 2 consecutive weeks You tolerated the current dose with minimal side effects Your fasting glucose (if diabetic) or HbA1c has plateaued above target When NOT to increase: You're experiencing persistent nausea, vomiting more than twice per week, or signs of dehydration You've had an episode of pancreatitis (current or past) You're planning surgery or a medical procedure in the next 4 weeks (GLP-1 agonists delay gastric emptying, which affects anesthesia risk) The maximum FDA-studied dose is 15 mg weekly

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Staying active helps support the energy boost from injections and accelerates visible changes
Exercise Regularly: Physical activity boosts circulation, aiding nutrient delivery to the skin
While there's no peer-reviewed data on why this happens, according to Rob Stransky, president of the telehealth provider NiceRx, this can happen because of how these drugs slow the body's gastric emptying process, or how food moves away from the stomach into the small intestine