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Type 2 Diabetes (Oral Therapy) Orforglipron ACHIEVE-3 directly demonstrated orforglipron 36 mg superiority over oral semaglutide 14 mg for HbA1c reduction (2.2% vs 1.4%) and weight loss (9.2% vs 5.3%) in type 2 diabetes
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Apoptosis was also evident in SLC25A39-deficient xenografts, supporting a mitochondrial dysfunction-mediated anti-LUAD effect
