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Notably, based on the results from part 1 of the ESSENCE trial, on 15 August 2025, the FDA approved semaglutide 2.4 mg for the treatment of adults with MASH with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis)

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First discovered in human plasma in the early 1970s, this molecule has since gained attention for its regulatory role in numerous biological pathways related to repair

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