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In the kidney, we observed widespread disruption in energy metabolism and multiple molecules involved in glycolysis, gluconeogenesis, and the TCA cycle were depleted, indicating a more global disruption in energy metabolism than has been previously appreciated

After H 2 O 2 treatment, CO23 strain was more able to counteract the oxidative stress indicating that these amino acid precursors helped CO23 against oxidants probably increasing GSH synthesis

The enzyme also keeps mitochondria efficient and helps it perform under stress

Venditti P, Di Stefano L, Di Meo S