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Another G s -type GPCR that functions in BAT to regulate lipolysis and thermogenesis is GPR3
Does not interact with known drug-metabolising enzymes, which reduces the probability of drug-drug interactions, but long-term metabolic consequences of sustained NNMT suppression in humans remain uncharacterised
Side effects are uncommon but may include mild discomfort or bruising at the injection site and occasional lightheadedness
External resources for researchers PubChem 5-Amino-1-methylquinolinium Open-access paper selective small-molecule NNMT inhibitors PubMed NNMT inhibition in preclinical metabolic research Related research products Disclaimer Used solely for in vitro experiments and cannot be: Used in clinical trials involving humans Administered to humans as part of an experiment or investigation Supplied to another party for human investigational use
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