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Several clinical trials and observational studies have examined metabolic changes associated with semaglutide treatment, though specific hormonal parameters including testosterone were not primary endpoints in most pivotal trials

At 5 mg/mL, it is 50 units

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2.6 Software Datasets containing PK and covariate data from each trial were converted to a format compatible with the modelling software NONMEM (ICON Development Solutions, Ellicott City, MD, USA), Version 7.3

After the indicated incubation times, reactions were quenched by adding 1LmL cold KPBS, followed by two additional washes in 1LmL cold KPBS using the multiLchannel pipette