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GLP-1R agonists have favorable long-term effects on renal function, particularly in patients with diabetic kidney disease (DKD)

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the GLP-1R / cAMP / PKA / BDNF mechanism and where it converges with HGF/c-Met downstream

Weight loss and RA outcomes A 2023 randomised controlled trial by Ranganath and colleagues assigned 40 RA patients with obesity to either a low-calorie diet intervention (1000-1500 kcal/day with meal replacements) or usual care for 12 weeks