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Patients should seek immediate medical attention if they experience severe, persistent abdominal pain, as this may indicate pancreatitis

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Extended-release exenatide (Bydureon BCise) has an apparent terminal half-life of approximately 2 weeks due to its depot formulation, with drug concentrations potentially persisting for 8-10 weeks after discontinuation

1 The drugmaker confirmed it submitted a marketing application for orforglipron to Chinas National Medical Products Administration at the end of 2025

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