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A new oral GLP-1 medication can help adults with obesity and Type 2 diabetes lose more weight and improve their blood sugar levels compared to a placebo, according to findings from the ATTAIN-2 trial led by a UTHealth Houston researcher

The relationship between the microbiome and sleep matters here because circadian rhythm disruption can affect appetite timing, microbial rhythms, SCFA production, and metabolic regulation

SURMOUNT-1 subgroup data from 2,542 women showed tirzepatide produced ~23% body weight reduction in peri/postmenopausal women vs 3% on placebo

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[1] It is not recommended for patients with severe gastroparesis