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IPF is characterized by excessive extracellular matrix (ECM) depositionmainly collagenwhich leads to irreversible scarring of the lung and progressive respiratory failure [11, 12]
La Organizacin Mundial de la Salud (OMS) reconoce la obesidad como una enfermedad crnica, compleja y multifactorial con una elevada prevalencia, ha subrayado el papel esencial de los tratamientos basados en GLP-1 y tambin insiste en la importancia de garantizar su acceso cuando estn clnicamente indicados
In addition, the professor said that only about 40% of patients maintain the use of the drug after a year, and emphasized that for diabetic and obese patients, regardless of treatment with any medication, it is still necessary to develop and maintain a healthy lifestyle to control the disease at the best level
As the Glutathione cream does not have a permanent effect on the skin, the extended use may damage the skin by acting harshly on it, and rashes may result
![Cardiovascular disease continuum-GLP-1 action. Adapted from [46]](https://www.researchgate.net/publication/357072789/figure/fig1/AS:1146405179654167@1650335702879/Cardiovascular-disease-continuum-GLP-1-action-Adapted-from-46.png)
