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Stay at the current dose until GI symptoms have resolved for at least two full weeks
In a January 2024 update, the FDA stated that its preliminary evaluation has not found evidence that GLP-1 RAs cause suicidal thoughts or actions, based on available clinical trial data and adverse event reports (FDA Drug Safety Communication, 2024)
Muscle loss slows your metabolism, weakens your bones, and can make weight regain more likely if you ever discontinue the medication
And this year, competitor Eli Lilly is slated for approval
Rats ( n = 14/group) were assigned to receive once-daily IP injections at the beginning of the onset of the dark cycle of vehicle (1 ml/kg), amylin (5 g/kg), GLP-1 (100 g/kg) or a combination of amylin and GLP-1 10,15,33,65,71,72,73,74
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