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The effects were most pronounced in overweight and obese individuals and when combined with lifestyle modifications like diet and exercise
Adding GLP-1-associated bone resorption to that baseline trajectory creates a compounding effect that's not yet fully characterized in long-term outcome data but that's biologically logical to worry about
Cht in gii rt cn thit cho hot ng khe mnh ca c th con ngi
Dinkla S, Peppelman M, Van Der Raadt J, Atsma F, Novotn VM, Van Kraaij MG, et al
Across randomized cardiovascular outcome trials and meta-analyses, SGLT2 inhibitors consistently reduce hospitalization for heart failure by approximately 3037% (hazard ratio [HR] 0.630.70), with benefits observed regardless of prior atherosclerotic cardiovascular disease status [6, 23]
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