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Individuals with higher body mass index (BMI) or greater subcutaneous fat may experience marginally altered pharmacokinetics, though tirzepatide has been studied across a wide range of body weights and remains effective
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Rietdijk CD, Perez-Pardo P, Garssen J, van Wezel RJA, Kraneveld AD
According to scientific data, long-term therapy often results in effective symptom management, with doses ranging from 0.4 to 0.8mg daily (1.2 to 2.4IU daily) [22]
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