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122 (Suppl): S3S10
Our experimental results demonstrated that the regulation of GGCT expression by Gln occurs neither at the transcriptional level nor via translational regulation, but is achieved at the post-transcriptional level by modulating the stability of GGCT mRNA
When NNMT is overactive (common in obesity), cells struggle with energy production and metabolic efficiency
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Similarly, studies conducted in diabetic patients reported that dapagliflozin-based therapy significantly improved systemic endothelial function and reduced both renal resistive index and aortic stiffness [163]
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