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Patients with vitamin B12 deficiency and concurrent renal or hepatic disease may require increased doses or more frequent administration of methylcobalamin

Int J Endocrinol (2015) 2015:147070

10.1186/s13229-016-0088-6 25

Adems, en la prctica clnica, muchas pacientes con fibromialgia e intestino irritable refieren mejora de sus sntomas digestivos (menor distensin, mejor trnsito) al usar enzimas digestivas de amplio espectro con las comidas, lo que contribuye a un mayor bienestar general