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The combined activation of CD4+ and CD8+ T cells in the pancreatic lymph nodes prepares these cells for the subsequent migration into the pancreas, where they ultimately destroy the cells

This helps regulate blood sugar levels by stimulating insulin release and reducing the production of glucagon, a hormone that raises blood sugar

F., Lingvay, I., Wadden, T

Amylin therapies Some drugs currently in development take a different approach, targeting receptors for a different hormone: amylin, which is co-secreted, alongside insulin, by the pancreas to slow gastric emptying, suppress glucagon secretion and signal feelings of fullness

This role extends beyond dispensing into active risk management