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The reason why has to do with the medication's effective life in your body

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A sub-study of this trial focused on GC through the use of continuous glucose monitoring (CGM) and the proportion of time within a tight predefined time in range (TIR) from 71 to 140 mg/dL at the end of the study was considerably more significant in the group of participants receiving either 10 or 15 mg TZP competed to the group taking insulin degludec (72, 73, 75)

No, semaglutide that has been frozen should be discarded immediately