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(3) Post-traumatic brain injury cognitive recovery

PMID: 25731775

In a Dextran Sulfate Sodium-induced colitis model, oral administration of ganoderic acid enriched beneficial microbial taxa, including Lactobacillus and Oscillospira , while reducing the abundance of pathogenic bacteria

Therapeutic strategies targeting this cycle -such as Nrf2 activators (sulforaphane), mitochondrial antioxidants (MitoQ), and AGE inhibitors (aminoguanidine)- highlight the dual role of OS as interventions early in DM, which can improve -cell function, while later-stage treatments primarily mitigate complications

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