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The data dont lietheres a substantial increase in men needing exogenous hormone therapies to combat endocrine dysfunction from conditions like obesity

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These findings highlight the direct impact of the temporary activation of the GLP-1-IL-6 axis in adipocytes, which contributes to regulating the overall balance of the metabolism of glucose and lipids in the body [120]

So the case for oral options isnt that injections are bad its optionality

J Craniofac Surg 33(8):e810e812 Hwang J, Lee YK, Burm JS (2017) Treatment of Tongue Lymphangioma with Intralesional Combination Injection of Steroid, Bleomycin and Bevacizumab