I lost 17% of my body weight and I've kept it off
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In early clinical trials, patients on GLP-1 agonists have achieved weight loss of 1520%, compared to the 510% typically seen with previous medications. Holistic approach to GLP-1 drugs Beyond weight loss, GLP-1 agonists have demonstrated the ability to reduce major cardiovascular events, combat fatty liver disease and alleviate obesity-related complications such as knee pain, sleep apnea, and acid reflux
2 GLP-1 is an incretin hormone produced by intestinal L cells that is responsible for up to 70% of insulin secretion in response to nutrient intake
Although the influence of sex chromosomes on skeletal muscle mass and fat deposition seems to be minor and age-dependent, it is relatively understudied, with the dominant driver of sex differences in these tissues and the brain pointing to gonadal hormone production [157, 160, 161]