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For oral B12 supplementation with a supplement like Cobalequin, 250 micrograms must be given once daily and continued initially for 12 weeks
Bibcode:1994ApEnM..60.1495K
However, they frequently cause gastrointestinal distress and can lead to significant muscle loss if not managed properly
The improvement in energy levels following B12 supplementation in deficient individuals reflects restoration of normal physiological function rather than a stimulant effect
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