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Thisse C, Degrave A, Kryukov GV, Gladyshev VN, Obrecht-Pflumio S, Krol A, Thisse B, Lescure A

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Dose reduction should be done gradually and should be done under medical surveillance

As a result, both modulation of NADPH oxidase to prohibit ROS overproduction and antioxidants supplementation have been reported as active strategies to prevent the deleterious effect of oxidative stress in hemodialysis patients [64]