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It should be noted that while the HIF pathway can induce antioxidant genes like SOD2 to maintain adaptive balance under acute hypoxia, this protective effect in chronic diseases like cancer may conversely aid malignant cells in resisting apoptosis, constituting another dimension of intervention complexity [501]
12-month shelf life when properly stored in a sealed container
10.1038/mi.2012.89 21
smFISH Dissected adult brains (2 months old) were embedded in OCT, frozen and stored at 80 C until use
So normal people don't really "store" it but most is not lost
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