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Next, we evaluated the proteases in cancer cells and demonstrated that the gasdermin D-cleaving variant induced lytic cell death in several cancer cell lines

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Hadjivassiliou M, Gibson A, Davies-Jones GA, Lobo AJ, Stephenson TJ, Milford-Ward A

For their ligandin function, GSTs bind a wide range of compounds in a non-catalytic manner at so-called L-sites, which are often distinct from the active site

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