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The beyond-use date indicated on the Tirzepatide ODT packaging represents the date beyond which the medication should not be used, as established by stability testing under specified storage conditions
123 , S28S37 (2010)
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However, GLP-1, in addition to various GLP-1R agonists, is a 300-fold stronger inducer of GSIS (4, 9) and does not produce the effects of glucagon to increase hepatic glucose production, which is thought to be a key pathogenic driver of T2DM (3)
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