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Zhang J, et al

Its cardiotoxicity-diminishing activity seems to be due to the removal of iron from ironanthracycline complexes, and thus it may reduce free radical formation

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Moffat, J

Additionally, baicalein, an active component from the traditional Chinese medicine Scutellaria baicalensis, functions as a potent iron chelator and inhibits erastin-induced Fe 2+ production under normal cellular conditions, potentially playing a key role in regulating organismal iron homeostasis and inhibiting Fenton reactions (71)