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The peptide works specifically on adipose tissue through beta-3 adrenergic receptor modulation, triggering lipolysis while inhibiting lipogenesis, without affecting growth hormone levels, insulin sensitivity, or other metabolic systems

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uncovered a significant increase in spurious transcripts originating from cryptic intragenic promoters in Dnmt3b KO (Neri et al., 2017) and suggesting that binding of DNMT3B to actively transcribing gene body is crucial for enhancing transcriptional fidelity