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Clinical considerations: All three products carry a boxed warning regarding the risk of thyroid C-cell tumors observed in rodent studies, contraindicating their use in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
Whiteside EJ, Boucaut KJ, Teh A, Garcia-Aragon J, Harvey MB, Herington AC
The counter-argument is that a second receptor pathway is a second source of variability in effect, in tolerability, and in long-term safety questions
10.1016/j.theriogenology.2014.10.002 51
KEY OBSERVATIONS MEDVis review responses are individualized and actually engage with specific patient feedback
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