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New England Journal of Medicine (2025) 2
Masiewicz, P., Brzostek, A., Wolaski, M., Dziadek, J
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Seek urgent help if depression includes thoughts of self-harm, feeling unsafe, or sudden changes in behavior
However, the development of selective KAR agonists and antagonists has lagged behind the development of NMDA and AMPA receptor ligands, largely due to cross-reactivity
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