Preservation of Insulin and Glucose Homeostasis Unlike growth hormone, which can cause insulin resistance and elevated blood glucose (diabetogenic effects), AOD-9604 has demonstrated no negative effects on carbohydrate metabolism
Higashi Y, Sukhanov S, Anwar A, Shai SY, Delafontaine P
Exclusion criteria included prematurity, being small for gestational age, neurological or psychiatric disorders, ADHD, movement disorders, syndromic short stature, additional pituitary hormone deficiency, known sleep disorder, known medical therapy for a chronic condition, or less than 6 months of growth hormone treatment
Urology 60 , 913918 (2002)
Medications are the most common initial treatment, although their effectiveness may diminish over time