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Agarwal A, Said TM, Bedaiwy MA, Banerjee J, Alvarez JG
In contrast, inhibition of autophagy under such conditions resulted in cellular damage and apoptosis ( Various types of autophagy have been recognized in mammalian cells, involving i) macroautophagy, ii) microautophagy and iii) chaperone-mediated autophagy, all of which act through the lysosome-dependent pathway but differ in the machinery used to deliver autophagic cargo to the lumen of lysosomes (Ravikumar et al., 2009
Illegal therapeutic marketing occurs when companies sell these same peptides with claims suggesting treatment of injuries, diseases, or conditions in humans without FDA approval
Combination approaches that couple GSH-triggered release with ferroptosis induction, immunotherapy, radiotherapy, or metabolic modulation represent promising strategies to overcome resistance Fig
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