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Glutathione Glutathione (GSH, gamma-glutamylcysteinylglycine) is the body's most abundant endogenous antioxidant, present in virtually all mammalian cells

Genetic polymorphisms in genes encoding matrix metalloproteinases, collagen synthesis enzymes, or inflammatory mediators could theoretically influence GHK-Cu responsiveness, though systematic investigations of pharmacogenetic determinants remain absent from current literature

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Animal model studies indicated that cisplatin may exhibit its own cardiotoxic properties by an increase in caspase-3 activity that leads to apoptosis of cardiomyocytes and subsequent drop of cardiac muscle contraction (129)