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They also point out that they cannot show a correlation between the dose of semaglutide prescribed and the incidence of NAION or that stopping semaglutide was associated with an improvement in NAION, both of which would be needed to suggest causation
In contrast, for those on GLP-1RAs therapy for 6 months or less, the intercepts were negative for age and positive for gender, but again, the estimates for age and sex did not yield significant results, indicating a lack of influence from these variables on weight changes
Ben: It's a fascinating analog
Whillier et al., 2009
The GLP-1 component slows gastric emptying, inhibits glucagon and dampens appetite via the satiety center in the hypothalamus
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