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GLP-1s should be discontinued for at least two months prior to becoming pregnant
Assessing the requirement of CD36 for GLP-2-mediated increases in intestinal-TG secretion are complicated by the increased fatty acid absorption (as shown by appearance of radiolabel in plasma), TRL-TG and TRL-apoB48 secreted by Cd36 / mice compared to wild-type controls (Hsieh et al., 2009)
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5 Lilly is running Phase 3 studies on orforglipron for the treatment of type 2 diabetes and for weight management in adults with obesity or overweight with at least one weight-related medical problem
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