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10.3345/kjp.2017.60.4.106 Korean J Pediatr
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Multifaceted roles of UFMylation in health and disease
With a median dose of 1000 mg metyrapone for 9 months, UFC and late-night salivary cortisol (LNSC) decreased quickly after the first month of treatment (67% and 57% from baseline), and sustained UFC normalization was observed up to 12 and 24 months (70% and 30% of patients had normalized UFC and LNSC at the last visit, respectively)
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