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Impact on Obesity-Related Gastrointestinal Complications GLP-1 agonists and dual agonists like tirzepatide can have both positive and negative effects on obesity-related gastrointestinal conditions

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

Though the FDA approved Novo Nordisks earlier obesity drug, Saxenda, for weight loss in adolescents in December 2020, theres greater interest in Wegovy since its injected weekly instead of daily and it has been shown to have greater effects on weight loss

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