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It has been proposed that the allelic variant might influence the stability of GSTP1-1/JNK complex and consequently JNK activity, depending on the redox status of the cell

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Abbreviations AhR: Aryl hydrocarbon receptor AR: Androgen receptor BPA: Bisphenol A BPAF: Bisphenol AF BPF: Bisphenol F BPS: Bisphenol S Cyp19a1: Cytochrome P450 family 19 subfamily A member 1 (aromatase) DDE: Dichlorodiphenyldichloroethylene DDT: Dichlorodiphenyltrichloroethane DEHP: Di(2-ethylhexyl) phthalate DNMTs: DNA methyltransferases E2: 17-Estradiol EE2: 17-Ethinylestradiol EEs: Environmental estrogens ER: Estrogen receptor alpha ER: Estrogen receptor beta EREs: Estrogen response elements GPER: G protein-coupled estrogen receptor HPG: Hypothalamic-pituitary-gonadal lncRNAs: Long non-coding RNAs MAPK: Mitogen-activated protein kinase mER: Membrane estrogen receptor miRNAs: MicroRNAs nER: Nuclear estrogen receptor PCBs: Polychlorinated biphenyls PCOS: Polycystic ovary syndrome PI3K: Phosphatidylinositol 3-kinase PPAR: Peroxisome proliferator-activated receptor gamma PR: Progesterone receptor ROS: Reactive oxygen species TR: Thyroid hormone receptor VTG: Vitellogenin ZEA: Zearalenone 3-HSD: 3-Hydroxysteroid dehydrogenase 17-HSD: 17-Hydroxysteroid dehydrogenase References Campbell CG, Borglin SE, Green FB, Grayson A, Wozei E, Stringfellow WT

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