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Very high doses (such as those used for cyanide poisoning) should be used with caution and only if the potential benefit outweighs the risk

The quinolinium structure of 5-Amino-1MQ is designed to fit the NNMT active site selectively, which is significant because SAM is used by many other enzymes that researchers do not intend to affect

Detection indicators: bone density (lumbar spine, hip), bone turnover markers (OC, CTX), bone microstructure (number, thickness, and gaps of bone trabeculae), and skeletal mechanical strength

While these symptoms have not been specifically attributed to AOD-9604 excess in published literature, the FDA advises treating any adverse reaction to a compounded product as reportable through MedWatch [8]