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Description

Repeated inadvertent ingestion of supratherapeutic doses may be especially dangerous, due to subacute depletion of hepatic glutathione stores

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It is sometimes used in medical research and is also known to be used by some athletes and bodybuilders for its potential performance-enhancing effects

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Previous results have shown that expression and activity of PGC-1 are regulated by AMPK and SIRT1 42

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However, dose-dependent gastrointestinal effects limit efficacy, so drugs with GLP-1 and GCG pharmacology can also target alternative pathways and may expand the therapeutic index (132)

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