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Many Zepbound patients carry a diagnosis of type 2 diabetes or prediabetes
The article says GLP-1 agonists stimulate appetite-suppressing neurons in the hypothalamus and slow gastric emptying, and that during menopause this may counteract the reduced satiety signaling caused by estrogen loss
Each dose increase essentially resets your side effect expectations because your body needs to adjust to the higher level of receptor activation
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