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Studies on rodents have shown GLP-1 receptor agonists can have antidepressant effects, but only with long-term use

Tirzepatide is a dual GLP-1/GIP receptor agonist thats similar to semaglutide

The PP2A regulatory subunit PPP2R2A controls NAD(+) biosynthesis to regulate T cell [PMID: 38889006] Laboratory literature summary: The PP2A regulatory subunit PPP2R2A controls NAD(+) biosynthesis to regulate T cell subset differentiation in systemic autoimmunity

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Du ToitGRobertsGSayrePHBahnsonHTRadulovicSSantosAFet alRandomized trial of peanut consumption in infants at risk for peanut allergy