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Clinical Trial Results The clinical trial SURMOUNT-5 (NCT05822830) of adults with obesity who did not have type 2 diabetes demonstrated that Zepbound patients had an average weight loss of 50.3 lbs (22.8 kg), which was 20.2% of their body weight, and a 7.2-inch ( 18.4 cm) reduction in waist circumference, at 72 weeks

This is particularly concerning given that both drug classes can independently contribute to bleeding risks [140]

By looking at the gene expression patterns, Li's team first found that the pathway that produces vitamin B12 was significantly altered in the skin bacteria of people with acne, compared with the skin bacteria of people without acne

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Patients often present with resistance to the initiation of an injectable agent