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Lets talk about the side effectsand more importantly, how long they tend to stick around

Clinicians can be reassured that the three GLP-1-based agents studied have comparable [GI] safety profiles when used in everyday practice, Wajd Alkabbani , PhD , an assistant professor at the University of Waterloo School of Pharmacy in Canada, told Healio

Limit alcohol consumption , which can worsen dehydration and lightheadedness, and be cautious with activities requiring alertness until symptoms resolve

In those with T2DM who continue to have an A1C above target despite dual/triple therapy with metformin and other antidiabetic agents, the GLP-1 receptor agonists and dual agonists are preferred injectable medications to insulin due to similar or even better efficacy in A1C reduction, lower risk of hypoglycemia, and cardiovascular and renal protective benefits

Poor sleep disrupts ghrelin and leptin levels, the primary hunger and satiety hormones, which can partially offset GLP-1 mediated appetite suppression