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Microglia, the resident immune cells in the CNS, function as brain macrophages and are essential in modulating neuroinflammation when activated under inflammatory conditions [100, 101]
in the U.K
Brouwers B, Rao G, Tang Y et al (2024) Incretin-based investigational therapies for the treatment of MASLD/MASH
Together, these forces erode mitochondrial function, damage DNA, and slowly push cells toward dysfunction and death [38, 39]
Activation of GLP-1R induces an increase in intracellular Ca 2+ in 40% of NTS astrocytes, while selective inhibition of astrocyte function in NTS abolishes exendin-4-induced inhibition of food intake (Reiner et al., 2016)
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