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The ratio of reduced (GSH) and oxidized (GSSG) glutathione is an important measure of a cells ability to maintain redox homeostasis

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[] At low temperatures, glucose metabolism via the Pentose phosphate pathway (PPP) pathway is also reduced, which glucose-6-phosphate dehydrogenase (G6PD), and NADPH reduces leading to the loss of the RBCs antioxidant activity during the storage

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