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The most dramatic result (mice returning to a body composition indistinguishable from lean age-matched animals) came from combining the inhibitor with a low-fat diet switch, and that study did not include a drug-alone arm

Oral administration of hydrolyzed collagen alleviates pain and enhances functionality in knee osteoarthritis: results from a randomized, double-blind, placebo-controlled study

This matters most where scar tissue limits function, such as tendon, ligament, and muscle injuries

J Neurochem 97(Suppl 1):148153

It can also help reduce acne scars and sun damage , making it an essential peptide for overall skin rejuvenation